Bioinformatics analysis on the SNP in promoter region of POLRMT gene in Guizhou local goat

In order to provide the basic information and scientific proof for better heredity selection of Guizhou Local goats, three goat breeds (Guizhou Write Goat, Guizhou Black Goat and Qianbei Ma Goat) were selected as the experimental subjects for exploring the influence between SNPs which located in the promoter region of POLRMT gene and meat quality. SNPs were screened by constructing the DNA pool, and variety bioinformatics softwares were used to predict the core region of the promoter, CpG island and transfer factors. The results showed that two SNPs (T-81A, T-289C) were found in POLRMT gene. Because of the two SNPs, the range of POLRMT gene core promoter changed, transcription factors disappeared, meanwhile, one CpG island increased.