Abstract: It is an effective way to control PCV-2 infection by vaccination and the study on PCV-2 vaccines is one of the hot research areas. Some commercial PCV -2 vaccines, including subunit vaccines, chimeric virus vaccines and inactivated vaccines, are available on the international market, and the inactivated vaccines have already been widely used in Chinese swine farms. This paper reviews the development of PCV-2 vaccines, the potential problems existing in the study. It may become a useful contributor to the control measures and design of novel vaccines for PCV-2.