Abstract: County agriculture is the basic component of national economy. Quantitative analysis of eco-efficiency of county agricultural economic system can provide decision basis to the regional agricultural resource planning and the agricultural sustainable development. Based on emergy analysis method，this paper measured the eco-efficiency of 67 counties in Guangdong province between 2000 and 2010. Spatial variation and grade division images were produced by ArcGis. The results showed that Guangdong county agricultural economic system had a good natural environment as well as a relative high output efficiency. The system had advantages in market exchange activities and gained the substaintial sustainable development capability. According to the research，we suggested to build Guangdong sustainable development agricultural demonstration area with“ Xinxing-Shixing-Fogang” counties as the radical center and the Yunan County and Jiaoling County as the minor center to promote the agricultural development of Yuexi and Yuedong area.