Abstract: Effects of different topping nodes on growth，yield and quality of melon cultivars of“ Nanhaimi” were investigated by soilless culture. The results showed that the fruit shape index of melon first decreased and then increased with topping node adding，and the single leaf area，soluble sugar content，central soluble solids content and edge soluble solids content increased gradually，while the single fruit weight and vitamin C content first increased and then decreased with topping node adding. A suitable topping node would improve yield and quality of melon. Through fully analyzing the effects of different topping nodes on the growth，yield and quality of melon，the reasonable topping node of melon was 26th. Therefore，the shoulder high of greenhouse for melon in tropics shall be 2 m.