Abstract: This paper used methods of empirical analysis and multi index evaluation with the quantitative evaluation model of coordinated development and gravity center transfer model to discuss the spatial-temporal evolution of coordinated development between land use and ecological environment in the Pearl River Delta from 1999 to 2008. The results indicated that the overall level of coordinated development degree was not high; the overall degree improved from 1999 to 2008, but declined in 2003-2004 in varying degrees except Shenzhen; obvious space difference was existed, economic developed area was much better than other areas; coordinated development degree of the Pearl River Delta had a tendency to transfer to the northeast during the research period. Therefore, land use and ecological environment coordinated development consciousness remained to be strengthened in the Pearl River Delta. Regional differences served as a reference model for the urban development. It is concluded that Pearl River mouth eastern area should adhere to sustainable coordination development strategy to play an exemplary role. Besides, the west area should insist on strengthening coordination development strategy to optimize land use pattern and strengthen regional cooperation.