Abstract: In recent years, under the framework of GMS, the cooperation between China and Cambodia is becoming wider, agriculture is an important field. Accurate agricultural information is essential to enable two sides to make informed decisions. Based on the agricultural knowledge, time series MODIS data and other data, the agricultural characteristics and the relationship with the flood were extracted and analyzed. The result showed that one cropping system was commonly employed in Cambodia. Double-cropping system was mainly distributed in the Mekong Delta. The starting date of growing season, the ending date of growing season and date of maximum NDVI generally occurred from July to September, from November to December and from May to June, respectively. Each year, the west -south monsoon occurring from May generally caused serious flood in Cambodia which then exerted great influence on the cropping patterns. Therefore, understanding the current status of flood inundation and its relationship with cropping practice in time and space was important. It was found that from the early May to middle September, the flood begin, and about two months later about 84% of crops began to grow. From middle August to middle November, about 58% of flood began to subside. About one month later, the peak of time series NDVI began to occur. From November to January of next year, about 76% of crop爷s growing season began to end.