Abstract: Effects of different ratioes of biogas slurry and chemical fertilizer on soil fertility, fruit yield and quality in litchi orchard were studied. The results showed that biogas slurry irrigation could increase the pH value of siol and organic matter content in soil by 0.37~0.77 and 0.30~2.88 g/kg respectively袁and could increase the soil alkaline hydrolytic N, available P and available K content in different degree. Compared with treatments of chemical fertilizer and no fertilizer, soil physical and chemical properties and soil fertility were significantly improved. After applied with biogas slurry, total soluble solid and total sugar of litchi fruits increased evidently, titratable acid content significantly reduced袁and litchi quality were obviously improved. The reasonable mixture of biogas fertilizer and chemical fertilizer was more effective to improve soil fertility, fruit yield and quality in litchi orchard.