Abstract: Using two orthogonal rotational regression combination design, research of new hybrid maize varieties in Gaorui 171 yield and planting density and nitrogen, phosphorus, potassium fertilizer application relationship, building mathematical models of the various factors and yield. The size effect on maize yield were Gaorui 171 planting density and amount of nitrogen, phosphorus and potassium. The great Gaorui 171 above 9 558 kg/hm2, yield of planting density and N, P, K fertilizer optimum combination scheme: the planting density of 41768~44395 strain/hm2, N 193.34~249.39 kg/hm2, P 128.90~179.79 kg/hm2, potassium 92.9~131.09 kg/hm2. Its purpose is to play the production potential, the largest species provide guidance to accelerate large area promotion.