Abstract: Non-host disease resistance is the most common form of disease resistance exhibited by plants against the majority of potentially pathogenic microorganisms. People think non-host plant recognized the pathogenic excitor and released resistance signal, nonhost resistance was triggered through resistance signal cascade amplification reaction, recent research find that some non-host resistance genes and few transcription factor participate non-host resistance response. This article summarized the mechanism of non-host resistance by expounding it's components and categories.