Abstract: 【Objective】The study was to investigate the epidemiology of pathogen of White Spot Syndrome（WSS）and Early Mortality Syndrome（EMS）of wild prawn in natural sea area. 【Method】The detection on the WSS and EMS viruses of wild shrimps collected from Daya Bay during 2018 and 2019 was performed by PCR detection method.【Result】The results showed that the average virus positive rate of WSS was 22.96% during 5 months’detection in 2018, and the virus positive rate was 0 in August. The average virus positive rate of WSS was 2.43% during 9 months’detection in 2019, and the virus positive rate was 0 in January and from August to October. The average virus positive rate of EMS was 29.93% in 2018, with the highest value of 63.04%. The average virus positive rate of EMS was 41.33% in 2019, with the highest value of 94.00%.【Conclusion】The time distribution of virus-carrying rate of WSS and EMS of wild shrimps in Daya Bay seemed to be irregular. The virus-carrying rate of WSS was in a lower level, but that of EMS was in a higher level.