Abstract: 【Objective】The study tried to select new soybean strains suitable for production and breeding in Suzhou areas, Anhui Province. 【Methhod】 The agronomic characters, quality, resistance and yield of 18 new soybean strains were compared, with Zhonghuang 13 as control.【Result】The results showed that Fuyun 10174 had the highest yield, followed by Xu 9601-2B, Shengdou 4, Fu 1610, Zheng 1307, Zheng 1427, Luo 4903, Zhonghuang 309, Shengdou 3, Zhonghuang 316, Han 12-38, the yield of which increased by 52.67%, 50.10%, 45.43%, 44.83%, 38.06%, 29.88%, 20.73%, 20.17%, 17.55%, 9.98% and 9.98%, respectively compared with that of the control cultivar Zhonghuang 13, and the differences reached significant levels. In terms of the quality results, Han 12-383, Zheng 1307, Shengdou 3 and Xu 9601-2B had better performance and the total protein and fat contents of them were 63.38%, 63.61%, 63.61% and 63.31%, all of which belonging to the double high strains. Han 12-204, Zhonghuang 316, Zheng 1307, Fuyun 10174 and Xu 9601-2B had better resistance to the prevailing strains SC3 and SC7 of soybean mosaic virus （SMV） and all of them were resistant varieties. 【Conclusion】Combined with the results of yield, quality and resistance, the following strains, Zhonghuang 316, Zheng 1307, Fuyun 10174 , Xu 9601-2B and Shengdou 3 are suitable for planting in Suzhou. These strains can be used as excellent germplasm resources in this region.