Abstract: 【Objective】The objective was to study the effect of 30% Xiange oceanic bioactive peptide pesticidefertilizer on sugarcane pests prevention, yield and sugar.【Method】With conventional compound fertilizer and 3% carbofuran granulated insecticide as control, a comparative test of the field effect of 30% Xiange pesticide fertilizer on sugarcane was carried out.【Result】The results showed that after the application of 30% Xiange pesticide-fertilizer for 90 d, the control rates on sugarcane borer in the two test points were 93.66% and 93.09%, respectively, which were significantly higher than the rates of 21.86% and 24.19% of the control. Before harvest, the reduction rates of sugarcane borer in the two test points under pesticide-fertilizer treatment were 6.21% and 5.10%, respectively, which were significantly lower than the rates of 36.25% and 34.55% of the control. The control rates of Xiange pesticide-fertilizer on sugarcane chafer in two test points were 91.34% and 100.00% respectively, which were significantly higher than the rates of 68.00% and 64.29% of the control. The yields of sugarcane treated with Xiange pesticide-fertilizer at two test points were 107 700 kg/hm2 and 108 000 kg/ hm2, respectively, with the sugar contents of 15.62% and 15.55%, respectively. The yield and sugar content of sugarcane treated with Xiange pesticide-fertilizer increased by 28.63% and 1.33% compared with those of the conventional control treatment. 【Conclusion】30% Xiange oceanic bioactive peptide pesticide-fetilizer has good effect on sugarcane pests control, which would obviously increase yield and sugar. It is worth being promoted and applied in sugarcane planting area.