Abstract: 【Objective】 The study was to grasp the fluctuations of mutton price among different regions in China, and develop scientific and reasonable price control policies to promote the healthy development of China's animal husbandry. 【Method】 With the quarterly data from March 2000 to September 2018, mutton price of main production area, main selling area and the national mutton market price were constructed as panel data of the price series, regional difference analysis of three price series was conducted by using panel vector autoregressive model (PVAR). 【Result】 Except for the main producing area of Heilongjiang Province, mutton prices of the main producing areas and the main selling areas have a bidirectional causal relationship with the national mutton price. The fluctuation of mutton prices in the main producing area and the main selling area has significant influence on the national mutton price. Compared with other provinces, Inner Mongolia, Sichuan and Shanghai have a leading role in the formation of the national mutton market price; the contribution rate of mutton price fluctuations in the main producing areas is generally higher than that in the main selling areas, and the price control policies cannot be imposed in all areas and should focus on mutton production. 【Conclusion】There is a great regional difference between the mutton price in the main producing area and the main selling areas, and regional differences need to be consider for the control policy of mutton price. The government should focus on strengthening support policies at the supply level, improving information release and early warning mechanism for the mutton market, and perfecting the traceability system for the entire industrial chain of the main production areas and main selling areas to ensure the sound operation of the mutton market.