Abstract: 【Objective】 The study was to improve the yield and quality of cucumber and its resistance to downy mildew and abiotic adversity.【Method】The resistance to cucumber downy mildew was identified by artificial inoculation at seedling stage and adult stage with 60 parent materials of cucumber inbred lines at home and abroad. By using the model of combination of laboratory identification and field selection，the cucumber varieties that meet the market demand were selected by taking Jinchun No.5 cucumber as the control. 【Result】 The new combination of HG2×HG5 cucumber with good comprehensive characters was screened. This variety has strong growth potential and good continuous fruit performance，with side vines and main vines bearing melons at the same time. The variety，crisp and juicy，has dark green skin，sharp thorns，slightly sweet taste and resistance to downy mildew，and shows strong adversity resistance in the field. It was registered by the Ministry of Agriculture and Rural Affairs as a non-major crop variety in 2018 with the registration number GPD Cucumber〔2018〕440036. 【Conclusion】This breeding method is simple and easy，which can not only shorten the cycle of disease resistance identification and improve the efficiency of breeding，but also reduce the waste of land，manpower and material resources，providing reference for grassroots breeders in the future.